North Carolina Intercity Bus Service

The North Carolina Department of Transportation’s (NCDOT’s) Intercity Bus program serves Winston-Salem, offering regional and long-distance travel across North Carolina and beyond. NCDOT’s Intercity Bus Network consists of 13 routes with over 50 stops throughout the state. Service is operated by Greyhound Lines and Sunway Charters. The service operates 7 days a week, 365 days a year. Buses are ADA accessible and include restroom facilities.

The Winston-Salem Intercity Bus stop is located at 100 W 5th St, 27101 Winston-Salem, NC and can be accessed via Winston-Salem Transit’s fixed route service.

Winston-Salem is along four subsidized Intercity Bus Routes: the High Country Gateway, the Triad-Danville Connector, the Piedmont Pass, and the Mid-State Express Intercity Bus Routes.

In addition to the four Subsidized Bus Routes that stop in Winston-Salem, there are several unsubsidized Intercity Bus Routes and service providers that also stop in Winston-Salem, which connect riders to several destinations inside and outside North Carolina.

Visit NCDOT’s North Carolina Intercity Bus Service webpage for all routes and details, including the link to purchase tickets.

All Intercity Bus details provided here have been updated and verified as current as of 9/30/2026.